LymphedemaV1, Main, Exploration, bibRecord, 00A937

[Isotope lymphography--possibilities and limits in evaluation of lymph transport].

Identifieur interne : 00A937 ( Main/Exploration ); précédent : 00A936; suivant : 00A938

[Isotope lymphography--possibilities and limits in evaluation of lymph transport].

Auteurs : A. Mostbeck [Autriche] ; H. Partsch

Source :

Wiener medizinische Wochenschrift (1946) [ 0043-5341 ] ; 1999.

RBID : pubmed:10378333

Descripteurs français

KwdFr :
- Agrégat d'albumine marquée au technétium (99mTc), Humains, Lymphoedème (imagerie diagnostique), Lymphoscintigraphie, Noeuds lymphatiques (imagerie diagnostique), Sensibilité et spécificité, Valeurs de référence, Épreuve d'effort.
MESH :
- imagerie diagnostique : Lymphoedème, Noeuds lymphatiques.
- Agrégat d'albumine marquée au technétium (99mTc), Humains, Lymphoscintigraphie, Sensibilité et spécificité, Valeurs de référence, Épreuve d'effort.

English descriptors

KwdEn :
- Exercise Test, Humans, Lymph Nodes (diagnostic imaging), Lymphedema (diagnostic imaging), Lymphoscintigraphy, Reference Values, Sensitivity and Specificity, Technetium Tc 99m Aggregated Albumin.
MESH :
- chemical : Technetium Tc 99m Aggregated Albumin.
- diagnostic imaging : Lymph Nodes, Lymphedema.
- Exercise Test, Humans, Lymphoscintigraphy, Reference Values, Sensitivity and Specificity.

Abstract

Quantitative isotopic lymphscintigraphy is based on a combination of transmission- and emission scintigraphy correcting the different depths of lymph nodes. This method allows an exact estimation of lymph-transport in legs during standardised stress. The depth-corrected uptake in the lymph nodes expressed in percentage of the injected dose (D%) reflects the lymph-transport. After s.c. injection of 1 mCi of 99 m Tc-microcolloid (Nanocoll) the prefascial lymph-transport and after intramuscular (i.m.) injection the subfascial lymph-transport can be assessed. The stress consists of 15 minutes walking on a horizontal treadmill at a speed of 3.2 km/h. After s.c. injection all types of lymphedema can be diagnosed (average uptake in lymphedema 2.0 +/- 2.5 D%, in normal legs 14.3 +/- 4.2 D%; p < 0.001). The subfascial transport is much lower, only 7.7% of the prefascial transport. In healthy legs the uptake after i.m. injections is 1.1 +/- 0.8 D%, in postthrombotic syndrome the uptake decreases to 0.2 +/- 0.16 D% (p < 0.02). Lymphscintigraphy after i.c. injection of the colloid reveals contradictory results. The uptake is very low only in lymphedema with involvement of the whole leg. In distal and in secondary lymphedema the uptake is near the normal range. The clearance rate of the tracer from the depot is not reliable for diagnosing lymphedema. Information may be gained concerning the following points: quantitative measurement of lymph transport, routine diagnosis of lymphedema, follow-up in lymphedema, assessment of pre- and subfascial lymph-transport in patients with venous diseases, angiodysplasias etc., documentation of therapeutic effects.

PubMed: 10378333

Affiliations:

Le document en format XML

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<term>Lymphoscintigraphy</term>
<term>Reference Values</term>
<term>Sensitivity and Specificity</term>
<term>Technetium Tc 99m Aggregated Albumin</term>
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<term>Lymphoscintigraphie</term>
<term>Noeuds lymphatiques (imagerie diagnostique)</term>
<term>Sensibilité et spécificité</term>
<term>Valeurs de référence</term>
<term>Épreuve d'effort</term>
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</keywords>
<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Lymph Nodes</term>
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Lymphoedème</term>
<term>Noeuds lymphatiques</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Exercise Test</term>
<term>Humans</term>
<term>Lymphoscintigraphy</term>
<term>Reference Values</term>
<term>Sensitivity and Specificity</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Agrégat d'albumine marquée au technétium (99mTc)</term>
<term>Humains</term>
<term>Lymphoscintigraphie</term>
<term>Sensibilité et spécificité</term>
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<front><div type="abstract" xml:lang="en">Quantitative isotopic lymphscintigraphy is based on a combination of transmission- and emission scintigraphy correcting the different depths of lymph nodes. This method allows an exact estimation of lymph-transport in legs during standardised stress. The depth-corrected uptake in the lymph nodes expressed in percentage of the injected dose (D%) reflects the lymph-transport. After s.c. injection of 1 mCi of 99 m Tc-microcolloid (Nanocoll) the prefascial lymph-transport and after intramuscular (i.m.) injection the subfascial lymph-transport can be assessed. The stress consists of 15 minutes walking on a horizontal treadmill at a speed of 3.2 km/h. After s.c. injection all types of lymphedema can be diagnosed (average uptake in lymphedema 2.0 +/- 2.5 D%, in normal legs 14.3 +/- 4.2 D%; p < 0.001). The subfascial transport is much lower, only 7.7% of the prefascial transport. In healthy legs the uptake after i.m. injections is 1.1 +/- 0.8 D%, in postthrombotic syndrome the uptake decreases to 0.2 +/- 0.16 D% (p < 0.02). Lymphscintigraphy after i.c. injection of the colloid reveals contradictory results. The uptake is very low only in lymphedema with involvement of the whole leg. In distal and in secondary lymphedema the uptake is near the normal range. The clearance rate of the tracer from the depot is not reliable for diagnosing lymphedema. Information may be gained concerning the following points: quantitative measurement of lymph transport, routine diagnosis of lymphedema, follow-up in lymphedema, assessment of pre- and subfascial lymph-transport in patients with venous diseases, angiodysplasias etc., documentation of therapeutic effects.</div>
</front>
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<affiliations><list><country><li>Autriche</li>
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<tree><noCountry><name sortKey="Partsch, H" sort="Partsch, H" uniqKey="Partsch H" first="H" last="Partsch">H. Partsch</name>
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<country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Mostbeck, A" sort="Mostbeck, A" uniqKey="Mostbeck A" first="A" last="Mostbeck">A. Mostbeck</name>
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Serveur d'exploration sur le lymphœdème

[Isotope lymphography--possibilities and limits in evaluation of lymph transport].

[Isotope lymphography--possibilities and limits in evaluation of lymph transport].

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.